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Search Results for " sigma-1 receptor antagonist 2 "

9

Compounds

Cat No. Product Name Synonyms Targets
T12911 Sigma-1 receptor antagonist 2 Sigma receptor
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
T16883 Sigma-2 receptor antagonist 1 Others
Sigma-2 receptor antagonist 1 is an antagonist of the sigma-2 (σ-2) receptor.
T1865 S1RA E-52862 Sigma receptor
S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor1R, Ki=17 nM), demonstrating significant selectivity over the sigma-2 receptor2R, Ki > 1000 nM).
T79499 KSK68 Histamine Receptor
KSK68 is a potent dual sigma-1 and histamine H3 receptor antagonist with potential analgesic activity and high affinity for H3 receptors, sigma-1, sigma-2 receptors.KSK68 can be used in the study of pain related diseases...
T79500 KSK94 Histamine Receptor
KSK94 is a specific H3 receptor antagonist that inhibits H3, sigma-1, and sigma-2 receptors , with Ki values of 7.9, 2958, and 75.2 nM, respectively, and can be used to study injurious pain and neuropathic pain.
T21788 BD 1008 dihydrobromide Sigma receptor
BD 1008 dihydrobromide is a selective antagonist of the sigma 11) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors.
T7352 Pridopidine ACR16,ASP2314,FR310826 Dopamine Receptor
Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.
T70809 BD 1008 Free Base
BD 1008 Free Base is a selective sigma receptor antagonist, with a reported binding affinity of Kᵢ = 2 ± 1 nM for the sigma-1 receptor and 4 times selectivity over the sigma-2 receptor.
T39176 PB28
PB28 is a cyclohexylpiperazine derivative that functions as a potent and highly selective agonist of the sigma 22) receptor, exhibiting a Ki (binding affinity) of 0.68 nM. At the same time, PB28 acts as an antagonist ...
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